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What Is PQQ?

By The CardioClear Team · Medically reviewed by Dr. Thomas Reiner, M.D., Board-Certified in Cardiology · Updated October 2026

Quick answer

PQQ is an antioxidant studied for supporting mitochondria. Its role in a formula. Remember that CardioClear is nutritional support for cardiovascular wellness in healthy adults — not a treatment for heart disease, high blood pressure or high cholesterol — and chest pain or other heart symptoms are a medical emergency; anyone on blood thinners or heart or blood-pressure medication should speak with a doctor first.

If you have been looking into what Is PQQ, you have probably met plenty of hype and hard-to-verify claims. PQQ is an antioxidant studied for supporting mitochondria. Here we take a calmer, evidence-minded look at what PQQ does, and explain how CardioClear can play a modest supporting role.

The importance of ingredient quality

With nutrients like CoQ10, Shilajit and PQQ, quality and form matter as much as the name on the label. Well-absorbed CoQ10, purified Shilajit and quality PQQ, all manufactured under GMP standards, point to a product that delivers what it promises. Cheap products may use poor-quality ingredients, inadequate amounts or unverified sourcing. Looking for named ingredients, sensible amounts and quality manufacturing helps separate genuine formulas from marketing, turning a promising ingredient list into real nutritional support.

CoQ10 and medication interactions

One of the most important things to know about CoQ10 is that it can interact with certain medications. It may reduce the effectiveness of blood thinners such as warfarin, and it may have additive effects with some blood-pressure medications. This is why anyone taking anticoagulants, blood-pressure or heart medication should consult their doctor before taking CoQ10. This is not a reason to avoid CoQ10, but a reason to involve a healthcare provider — and a key part of using any heart-support supplement responsibly and safely.

Traditional use versus modern evidence

Shilajit has a long history of traditional use, while CoQ10 and PQQ are more modern, research-driven ingredients. Traditional use is a valuable starting point, reflecting generations of observation, but it is not the same as rigorous evidence. Modern research on these ingredients is studied and ongoing, with effects that tend to be supportive and gradual. An honest view holds both together: respecting tradition while being realistic about current evidence, and presenting ingredients as nutritional support rather than proven cures for any condition.

Where CardioClear fits in

CardioClear is a once-daily capsule built around three researched ingredients — Coenzyme Q10 (CoQ10), Shilajit Extract and PQQ — chosen to support the cellular energy and antioxidant protection the heart relies on. In the context of what Is PQQ, it is best seen as one supportive habit within a broader routine of a heart-healthy diet, regular activity, not smoking and medical care. It supports cardiovascular wellness in healthy adults and is not a substitute for a healthy lifestyle or for medical care, and it does not treat or prevent any disease. Cautions to know.

Reading a heart-supplement label

A trustworthy heart supplement names every ingredient and discloses amounts, rather than hiding behind a proprietary blend. The label should state serving size, list allergens, and provide manufacturer details. Checking for GMP manufacturing, quality ingredient forms and clear labelling helps you judge quality. CardioClear names all three of its ingredients — CoQ10 100mg, Shilajit extract and PQQ 10mg — with amounts on the current label, reflecting the transparency an informed, safety-conscious consumer deserves.

What CoQ10 is not

It is important to be clear about what CoQ10 is not. It is a nutrient that supports cellular energy and antioxidant protection — not a drug, and not a treatment for heart disease, high blood pressure, high cholesterol or any condition. It does not replace prescribed medication, and no one should stop or change heart medication to take it. Understanding CoQ10 as supportive nutrition, used alongside a heart-healthy lifestyle and medical care, keeps expectations realistic and use safe and sensible.

How much CoQ10 is sensible

CoQ10 is commonly supplemented in the range of around 100mg to 200mg daily, though needs and research vary. CardioClear provides CoQ10 at 100mg, a sensible, commonly studied amount, alongside PQQ at 10mg and a Shilajit extract. More is not automatically better, and quality and absorption matter as much as the number. For anyone with a health condition or on medication, a doctor can advise on what is appropriate. Sensible amounts of quality ingredients, used consistently, are the goal.

Frequently asked questions

What is PQQ?

PQQ (pyrroloquinoline quinone) is an antioxidant compound studied for supporting mitochondria, the energy factories inside cells. It complements CoQ10 by supporting cellular energy and protecting cells from oxidative stress.

Can I take CardioClear with heart or blood-pressure medication?

Only with medical guidance. CoQ10 can interact with blood thinners (such as warfarin) and some blood-pressure medications. Consult your doctor or pharmacist before combining it with any heart, blood-pressure or anticoagulant medication.

Are the ingredient amounts disclosed?

Yes. CardioClear names all three ingredients openly — CoQ10 100mg, Shilajit extract and PQQ 10mg — with amounts on the current product label, rather than hiding behind a vague proprietary blend.

Key takeaways

  • What PQQ does.
  • Its role in a formula.
  • Cautions to know.
  • CardioClear is nutritional support for cardiovascular wellness in healthy adults — it is not a treatment for heart disease or any condition.
  • Chest pain or other heart symptoms are an emergency; consult a doctor before use if you take blood thinners or heart or blood-pressure medication.

Support your heart the honest way

CardioClear brings three researched ingredients together in one daily capsule — nutritional support for cardiovascular wellness, alongside your diet, activity and doctor.

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Medically reviewed by Dr. Thomas Reiner, M.D.
Board-Certified in Cardiology · Reviewed October 2026

Our content is written by the CardioClear editorial team and reviewed for accuracy against current guidance from bodies such as the American Heart Association, Mayo Clinic, Cleveland Clinic and the NIH. It is educational and is not a substitute for personal medical advice. Our editorial policy.

Medical disclaimer: This article is educational and not medical advice. CardioClear is a dietary supplement and is not intended to diagnose, treat, cure or prevent heart disease, high blood pressure, high cholesterol or any disease. It is for adults. Chest pain, shortness of breath, palpitations, fainting or other heart symptoms are a medical emergency — call your local emergency number or seek immediate care. CoQ10 may interact with blood thinners and some blood-pressure medications; if you take any heart, blood-pressure or prescription medication, or are pregnant or breastfeeding, consult your doctor before use. Never stop or change prescribed medication based on this content.
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